Tiphaine Le Roy

The chemorepellent effect of metformin limits bacterial penetration into mammalian mucus by altering bacterial motility

This study shows metformin acts as a bacterial chemorepellent, reducing bacterial penetration into mucus by altering motility and chemotaxis.

Disruption of IgA-mediated aggregation at weaning favors mucus encroachment by commensal bacteria

This study shows that IgA-mediated bacterial aggregation at weaning prevents mucus penetration by commensal bacteria, while its disruption allows deeper bacterial encroachment.

Spatial characterization of microbiota profiles along the gut in a widely used mouse model: effects of high-fat diet and fructooligosaccharides

This study characterizes gut microbiota composition along the gastrointestinal tract in mice under high-fat diet and prebiotic conditions, revealing species-specific responses and challenges the translational relevance of rodent models.