Cancer BiologybioRxivPreprint
Multi-hit STAG2 mutations define a high-risk subset of MDS and reveal convergent evolutionary targeting of cohesin
Eno-obong Udoh, Yi Chen, Matteo D’Addona…·Aaron D. Viny
The paper identifies multi-hit STAG2 mutations in MDS patients, showing they are associated with worse outcomes and suggest convergent evolutionary targeting of the cohesin gene.
DOI 10.64898/2026.09.02.749005