Author

Eno-obong Udoh

Cleveland Clinic

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Aaron D. VinyiD· 2 shared Jane Jialu XuiD· 2 shared Valeria VisconteiD· 2 shared Viviana ScocaiD· 2 shared Alexander Fisher· 1 shared Anabella Maria D. GalangiD· 1 shared Besmira Alija· 1 shared Claudia GebhardiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersCancer Biology

Aaron D. VinyORCID

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2 papers

Recent·Most cited

Multi-hit STAG2 mutations define a high-risk subset of MDS and reveal convergent evolutionary targeting of cohesin

Eno-obong Udoh, Yi Chen, Matteo D’Addona, Edna M. Stewart, Rong Deng, Felipe de Almeida Sartori, Serhan Ünlü, Zachary Brady, Ruowei Zhu, Xiaoyi Cheng, Viviana Scoca, Jane J Xu, Sergei R. Doulatov, Karl S. Theil, David S. Bosler, , Aaron D. Viny

The paper identifies multi-hit STAG2 mutations in MDS patients, showing they are associated with worse outcomes and suggest convergent evolutionary targeting of the cohesin gene.

bioRxiv · Sep 3, 2026 · PreprintCancer Biology

Altered chromatin accessibility mediated by somatic cohesin mutations amplifies FLI1-Menin output to promote leukemogenesis

Jane Jialu Xu, Viviana Scoca, Yi Chen, Yingqian Ada Zhan, Alexander Fisher, Eno-obong Udoh, Sebastian Fernando, Besmira Alija, John Pantazi, Varun S. Sudunagunta, Edna Stewart, Anabella Maria D. Galang, Michael Williams, Govind Bhagat, Claudia Gebhard, , Aaron D. Viny

This study shows that cohesin mutations alter chromatin accessibility, enhancing FLI1-Menin interaction and promoting leukemogenesis through therapeutic vulnerabilities.

bioRxiv · Apr 1, 2025 · PreprintCancer Biology