Edna M. Stewart

The paper introduces ecCLIP for high-resolution RBP binding maps and Pythia for structure-aware RNA-protein interaction modeling, improving RNA half-life prediction and variant effect assessment.

The paper identifies multi-hit STAG2 mutations in MDS patients, showing they are associated with worse outcomes and suggest convergent evolutionary targeting of the cohesin gene.

This study investigates how Stag2-dependent chromatin remodeling influences Gata1's function in erythropoiesis, revealing its role in lineage-specific gene regulation and dyserythropoiesis in MDS.

This study shows that polyamines regulate cell fate by altering chromatin structure through interactions with histone-modifying enzymes.

Long-read sequencing with the knock-knock pipeline profiles CRISPR knock-in repair, finding perfect homology-directed repair is often a minority of integration events and mis-integration varies by context.