Author

David S. Bosler

Cleveland ClinicORCID 0000-0002-5787-6869Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:differential expression· 1 Organism:human· 1 Approach:statistical model· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Aaron D. VinyiD· 1 shared Edna M. StewartiD· 1 shared Eno-obong Udoh· 1 shared Felipe de Almeida SartoriiD· 1 shared Jane J XuiD· 1 shared Jaroslaw Pawel MaciejewskiiD· 1 shared Karl S. Theil· 1 shared Matteo D’AddonaiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Aaron D. VinyORCID

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1 paper

Recent·Most cited

Multi-hit STAG2 mutations define a high-risk subset of MDS and reveal convergent evolutionary targeting of cohesin

Eno-obong Udoh, Yi Chen, Matteo D’Addona, Edna M. Stewart, Rong Deng, Felipe de Almeida Sartori, Serhan Ünlü, Zachary Brady, Ruowei Zhu, Xiaoyi Cheng, Viviana Scoca, Jane J Xu, Sergei R. Doulatov, Karl S. Theil, David S. Bosler, , Aaron D. Viny

The paper identifies multi-hit STAG2 mutations in MDS patients, showing they are associated with worse outcomes and suggest convergent evolutionary targeting of the cohesin gene.

bioRxiv · Sep 3, 2026 · PreprintCancer Biology