Author

Vladimir Despic

Goethe University FrankfurtORCID 0000-0002-1589-2596Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Vladimir Despic1 paper · Goethe University Frankfurt

Biology Disciplines

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Bioinformatics· 1 Genomics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Approach:experimental assay· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Assay:proteomics· 1 Assay:Ribo-seq· 1

Frequent Co-Authors

Michaela Müller-McNicolliD· 2 shared Andrea RentmeisteriD· 1 shared Anke BuschiD· 1 shared Anna OrekhovaiD· 1 shared Ben R HawleyiD· 1 shared Christina KalkiD· 1 shared Françoise DebartiD· 1 shared Hani GoodarziiD· 1 shared

Activity by Year

2019-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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2 shared papersBioinformatics

Michaela Müller-McNicollORCID

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3 papers

Recent·Most cited

BioinformaticsbioRxivPreprintAug 19, 2026

The extended Split-ORF pipeline: Prediction and evaluation of Split-ORFs using Ribo-seq data

Christina Kalk, Justin Murtagh, Vladimir Despic…·Marcel H. Schulz

The paper improves the Split-ORF pipeline to analyze Ribo-seq data, identifies over 14,000 candidate Split-ORF transcripts, and finds many show significant Ribo-seq coverage across cell types and diseases.

DOI 10.64898/2026.05.22.727176

𝕏 PostBluesky

GenomicsSTAR ProtocolsPeer-reviewedJul 17, 2026

iCLIP3: A streamlined, non-radioactive protocol for mapping protein-RNA interactions in cellular transcripts at single-nucleotide resolution

Vladimir Despic, Melina Klostermann, Anna Orekhova…·Michaela Müller-McNicoll

The paper introduces iCLIP3, a streamlined protocol for mapping RBP-RNA interactions at single-nucleotide resolution, with improvements in visualization, RNA isolation, and multiplexing.

DOI 10.1016/j.xpro.2026.104704

proteomicsexperimental assay

𝕏 PostBluesky

Molecular BiologyNature Chemical BiologyPeer-reviewedFeb 18, 2019

The RNA demethylase FTO targets m6Am in snRNA to establish distinct methyl isoforms that influence splicing

Jan Mauer, Miriam Sindelar, Vladimir Despic…·Samie R. Jaffrey

This study shows FTO demethylates m2-snRNA to regulate splicing by controlling reversible methylation of snRNAs.

268 citationstop 1%

snRNA-seqstatistical model

𝕏 PostBluesky