Melina Klostermann

The paper introduces iCLIP3, a streamlined protocol for mapping RBP-RNA interactions at single-nucleotide resolution, with improvements in visualization, RNA isolation, and multiplexing.

The paper identifies RNA-dependent proteins in cell division using R-DeeP, revealing new interactions and phosphorylation events involving AURKA, KIFC1, and TPX2.

This study identifies PUN motifs in yeast Loc1p that cooperate to catalyze RNA folding and drive phase separation, suggesting a role in RNA and DNA-related processes across species.

The paper evaluates how RNA-Seq library characteristics affect alternative splicing analysis using MAJIQ and recommends optimal parameters for improved sensitivity and precision.

racoon_clip processes iCLIP and eCLIP data to extract single-nucleotide RNA binding signals, providing automated analysis and visualization tools.

This study shows that PURA depletion affects posttranscriptional regulation and P-body formation, linking PURA Syndrome to neurodevelopmental disorders.