David B. Soffar

This study shows that cofilin regulates postsynaptic actin organization and neuromuscular junction function in a Drosophila nemaline myopathy model, leading to impaired neurotransmission.

This study shows that Drosophila Tropomodulin is essential for actin-dependent processes in myofiber assembly and maintenance, leading to myopathy-related phenotypes when disrupted.

This study shows that loss of Drosophila Cofilin disrupts sarcomere structure and function, leading to myopathy, and that proteasome activation can delay muscle deterioration.