Peter J. Carman

This paper uses cryo-EM to solve high-resolution structures of actin-bound myo1c with and without ADP, revealing unique actin-binding orientation, ADP release pathway, and power stroke trajectory.

This paper identifies design principles for modifying Hsp104 to enhance its therapeutic potential by tuning its collaboration with Hsp70 and Hsp40.

This study shows that Drosophila Tropomodulin is essential for actin-dependent processes in myofiber assembly and maintenance, leading to myopathy-related phenotypes when disrupted.

This study reveals structural insights into the RSC chromatin remodeling complex by showing how ARP binding induces conformational changes and enhances nucleosome remodeling.