Author

Chad S. Hunter

University of AlabamaORCID 0000-0002-1644-447XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:statistical model· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Organism:mouse· 2 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

Adam R. WendeiD· 2 shared Andrew Nafzinger· 1 shared Anil Kumar ChallaiD· 1 shared Charles Edward ChalfantiD· 1 shared Daniel StephensoniD· 1 shared Ernesto Satoshi NakayasuiD· 1 shared Haifa A. AlsharifiD· 1 shared Hayden H. Bickerton· 1 shared

Activity by Year

2019-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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2 shared papersCell Biology

Adam R. WendeORCID

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Author profile →

3 papers

Recent·Most cited

Tomosyn-2 Regulates Postnatal β-Cell Expansion and Insulin Secretion to Maintain Glucose Homeostasis.

Katherine C. Perez, Justin Alexander, Md Mostafizur Rahman, Haifa A. Alsharif, Yanping Liu, Jeong‐a Kim, Chad S. Hunter, Thanh Minh Nguyen, Sushant Bhatnagar

This study identifies Tomosyn-2 as a regulator of β-cell maturation, showing its role in balancing proliferation and function during postnatal development.

Diabetes · Apr 20, 2026Peer-reviewedCell Biology

ER Stress-Induced beta-Cell Apoptosis is Linked to Novel Select Lipid Signaling at the Transcriptional Level: Implications in T1D Development

XIAOYONG Y. LEI, Anil Kumar Challa, Susan E. Nozell, Tomader Ali, Daniel Stephenson, Andrew Nafzinger, Chad S. Hunter, Adam R. Wende, Ernesto Satoshi Nakayasu, Ying Gai, Charles Edward Chalfant, Sasanka Ramanadham

This study identifies a novel lipid signaling pathway involving iPLA2β that links ER stress to β-cell apoptosis in T1D, revealing transcriptional regulation by iDLs and potential therapeutic targets.

bioRxiv · Mar 6, 2026 · PreprintCell Biology

Prolactin Receptor Signaling Regulates a Pregnancy-Specific Transcriptional Program in Mouse Islets

Mark E. Pepin, Hayden H. Bickerton, Maigen Michelle Bethea, Chad S. Hunter, Adam R. Wende, Ronadip R. Banerjee

This study identifies transcriptional regulators and networks mediating islet adaptation during pregnancy through transcriptomic analysis of beta-cells in mice.

Endocrinology · Mar 11, 2019Peer-reviewedBioinformatics