Author

Alexandra Melton

Tulane UniversityORCID 0000-0002-1671-2905Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1 Assay:scRNA-seq· 1 Approach:wet-lab / biochemical assay· 1

Frequent Co-Authors

Janet E. McCombsiD· 1 shared Jay K. KollsiD· 1 shared Joseph P. HoffmanniD· 1 shared Kejing SongiD· 1 shared Krista Ferrari· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

5 top collaborators · 10 mutual co-author links

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1 shared paperImmunology

Janet E. McCombsORCID

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1 paper

Recent·Most cited

ImmunologybioRxivPreprintJan 24, 2026

Single-Cell RNA Sequencing Reveals Commensal Microbes Amplify Sex-Specific Immune Programming in the Murine Lung

Alexandra Melton, Krista Ferrari, Joseph P. Hoffmann…·Janet E. McCombs

This study uses scRNA-seq and flow cytometry to show that commensal microbes amplify sex-specific immune differences in the murine lung, with males showing myeloid bias and females lymphocyte skewing under SPF conditions.

1 citation

mousescRNA-seq