The Immune Factors Driving DNA Methylation Variation in Human Blood
Jacob Bergstedt, Sadoune Ait Kaci Azzou, Kristin Tsuo, Anthony Jaquaniello, Alejandra Urrutia, Maxime Rotival, David T S Lin, Julia L. MacIsaac, Michael Steffen Kobor, Matthew L. Albert, Darragh Duffy, Étienne Patin, Lluís Quintana‐Murci, Laurent Abel, Andrés Alcover, , Christophe Zimmer
This study identifies factors influencing DNA methylation variation in human blood, showing that cytomegalovirus infection and aging drive methylation changes, with cellular composition and DNA sequence as key predictors.
Nature Communications · Oct 6, 2022Peer-reviewedGenomics