Breanna R. Dooling

This study uses microglia-containing Alzheimer's disease brain organoids to monitor Aβ aggregation and cellular viability, identifying age-dependent disease-associated phenotypes.

This study shows that trisomy 21 cerebral organoids exhibit Alzheimer's disease amyloid and apoE co-pathologies, with apoE playing a key role in the disease process.

This study shows that overexpressing Kif11 rescues cognitive and synaptic deficits in Alzheimer's disease models.