Author
University Medical Center UtrechtORCID 0000-0001-6731-6657Unclaimed ORCID profile · follow to get notified of new preprints
5 papers
Recent·Most cited
Lucie A.G. van Leeuwen, Silvia Casanova, Oisharja Rahman…·Hayley J. Sharpe
The paper develops FlyPer, a Drosophila H2O2 biosensor toolkit, to measure subcellular H2O2 dynamics in vivo, revealing tissue-specific redox patterns during development and stress.
Simona Jole Anna Lafirenze, Bastiaan van Gerwen, Ajit I. Quirindongo…·Geert J.P.L. Kops
This study shows that chromosomal instability (CIN) can both promote and suppress tumor formation depending on its level, with high CIN acting non-cell-autonomously to drive tumor relapse.
Marieke R. Wensveen, Aditya A. Dixit, Robin van Schendel…·Aniek Janssen
The paper shows that DSBs in facultative heterochromatin require dUtx-mediated loss of H3K27me3 for repair by promoting DSB movement outside polycomb bodies.
Yuheng Huang, Yi Gao, Kayla Ly…·Yuh Chwen G. Lee
The paper investigates how polymorphic transposable elements (TEs) influence meiotic recombination rates in Drosophila by analyzing crossover frequencies in strains with distinct TE profiles.
Apfrida Kendek, Arianna Sandron, Jan-Paul Lambooij…·Aniek Janssen
This study shows that dGcn5-mediated H3K9ac enrichment at heterochromatic DSBs is essential for their movement to the periphery and proper repair.