Author

Jesús Gómez-Escudero

Centro de Biología Molecular Severo OchoaORCID 0000-0002-1710-2084Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Anna MinelloiD· 1 shared Anne Vincent‐SalomoniD· 1 shared Antonio GalarretaiD· 1 shared Aura CarreiraiD· 1 shared Charlotte A. MartiniD· 1 shared Dominique Stoppa‐LyonnetiD· 1 shared Elodie GirardiD· 1 shared Evgeny ImyanitoviD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Anna MinelloORCID

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1 paper

Recent·Most cited

Cancer BiologyNature CommunicationsPeer-reviewedDec 10, 2025

A recurrent pathogenic BRCA2 truncating variant reveals a role for BRCA2-PCAF complex in modulating NF-κB-driven transcription

Anna Minello, Jesús Gómez-Escudero, Sree Rama Chaitanya Sridhara…·Aura Carreira

The paper investigates a BRCA2 truncating variant's effect on NF-κB-driven transcription by showing it disrupts the BRCA2-PCAF complex, reducing histone acetylation and impairing cell migration.

2 citations

humanbulk RNA-seq

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