Attachment of the RNA degradosome to the inner cytoplasmic membrane of Escherichia coli prevents wasteful degradation of rRNA intermediates in ribosome assembly.
Lydia Hadjeras, Marie Bouvier, Isabelle Canal, Leonora G. Poljak, Quentin Morin‐Ogier, Carine Froment, Odile Burlet‐Schiltz, Lina Hamouche, Laurence Girbal, Muriel Cocaign‐Bousquet, Agamemnon J. Carpousis
This study shows that attaching RNase E to the inner cytoplasmic membrane in E. coli prevents the degradation of rRNA intermediates during ribosome assembly, explaining the evolutionary conservation of this localization.
bioRxiv · Jun 14, 2022 · PreprintMolecular Biology