Odile Burlet‐Schiltz

Dynamic membrane organization coordinates protein-O-mannosylation and proteostasis in mycobacteria.

The paper identifies a dynamic membrane platform in mycobacteria that coordinates protein-O-mannosylation and proteostasis through a hierarchically organized network.

A generalizable normalization framework to decouple protocol and instrument effects: Application to high-sensitivity proteomics multicentric study (PME13)

This paper introduces a normalization framework to decouple protocol and instrument effects in multicenter proteomics studies, demonstrating its application to the PME13 dataset.

Red bone marrow hosts metabolically active anucleate adipocytes that support hematopoiesis

The paper isolates and characterizes human regulatory bone marrow adipocytes, showing they are anucleate, metabolically active, and support hematopoiesis.

Drosophila melanogaster miPEP8 regulates cell size through its interaction with ref(2)P/p62

This study identifies miPEP8 as a regulator of cell size in Drosophila by interacting with ref(2)P/p62 and modulating autophagy.

ST8SIA4-mediated polysialylation is critical for CCR2-driven monocyte egress from the bone marrow

This study identifies ST8SIA4-mediated polysialylation as essential for CCR2-driven monocyte egress from the bone marrow, revealing a novel regulatory mechanism in immune cell trafficking.

Revealing the unexpected interplay between the Proteasome Activator PA200 and the immunoproteasome

This paper reveals structural and functional differences in PA200 interaction with the immunoproteasome (i20S) compared to the standard proteasome (s20S), showing PA200 enhances i20S activation and regulates its gene expression.

Integrative in vivo analysis of the ethanolamine utilization bacterial microcompartment in Escherichia coli.

This study characterizes the ethanolamine utilization BMC in E. coli using genetic, omics, and modeling approaches, revealing ethanolamine as a dual carbon and nitrogen source.

The human and mouse dendritic cell receptor DCIR binds to LRP1 N-glycans containing terminal galactoses, including the α-Gal antigen

This study identifies LRP1 N-glycans with terminal galactoses as ligands for DCIR, revealing its specificity in immune regulation and potential therapeutic applications.

The intrinsically disordered region of the E3 ubiquitin ligase TRIP12 induces the formation of chromatin condensates and interferes with DNA damage response.

This study shows TRIP12's intrinsically disordered region drives chromatin condensate formation, disrupting DNA damage response and genome accessibility.

Long non-coding RNA Neat1 and paraspeckle components are translational regulators in hypoxia.

The paper identifies Neat1 and paraspeckle components as translational regulators that facilitate IRES-dependent translation during hypoxia in mouse cardiomyocytes.

Attachment of the RNA degradosome to the inner cytoplasmic membrane of Escherichia coli prevents wasteful degradation of rRNA intermediates in ribosome assembly.

This study shows that attaching RNase E to the inner cytoplasmic membrane in E. coli prevents the degradation of rRNA intermediates during ribosome assembly, explaining the evolutionary conservation of this localization.

A comprehensive LFQ benchmark dataset on modern day acquisition strategies in proteomics

The paper presents a comprehensive benchmark dataset for evaluating label-free quantification methods across various proteomics acquisition strategies.

RIOK2 phosphorylation by RSK promotes synthesis of the human small ribosomal subunit

The paper shows RSK phosphorylates RIOK2, promoting pre-40S particle maturation and ribosome synthesis in human cells.