Author

Laurence Girbal

Centre National de la Recherche ScientifiqueORCID 0000-0002-8773-4829Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:bacteria (other)· 1 Assay:bulk RNA-seq· 1 Organism:E. coli· 1 Research Focus:gene regulatory network inference· 1 Approach:statistical model· 1

Frequent Co-Authors

Muriel Cocaign‐BousquetiD· 2 shared Agamemnon J. CarpousisiD· 1 shared Alfredo BensoiD· 1 shared Angela ReiD· 1 shared Carine FromentiD· 1 shared Gianfranco Michele Maria PolitanoiD· 1 shared Isabelle Canal· 1 shared Kaspar ValgepeaiD· 1 shared

Activity by Year

2022-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersSystems Biology

Muriel Cocaign‐BousquetORCID

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2 papers

Recent·Most cited

Systems-level analysis identifies protein-RNA interactions contributing to autotrophy of Clostridium autoethanogenum

Angela Re, Gianfranco Michele Maria Politano, Kristina Reinmets, Alfredo Benso, Laurence Girbal, Muriel Cocaign‐Bousquet, Kaspar Valgepea

The paper identifies genome-wide protein-RNA interactions in Clostridium autoethanogenum that contribute to autotrophy using a combination of experimental and computational methods.

bioRxiv · Dec 21, 2025 · PreprintSystems Biology

Attachment of the RNA degradosome to the inner cytoplasmic membrane of Escherichia coli prevents wasteful degradation of rRNA intermediates in ribosome assembly.

Lydia Hadjeras, Marie Bouvier, Isabelle Canal, Leonora G. Poljak, Quentin Morin‐Ogier, Carine Froment, Odile Burlet‐Schiltz, Lina Hamouche, Laurence Girbal, Muriel Cocaign‐Bousquet, Agamemnon J. Carpousis

This study shows that attaching RNase E to the inner cytoplasmic membrane in E. coli prevents the degradation of rRNA intermediates during ribosome assembly, explaining the evolutionary conservation of this localization.

bioRxiv · Jun 14, 2022 · PreprintMolecular Biology