Author

Yvonne D. Krom

Leiden University Medical CenterORCID 0000-0002-1719-5014Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell-cell communication· 1 Assay:ChIP-seq· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Assay:Hi-C· 1 Organism:mouse· 1

Frequent Co-Authors

Alexandra D. GurzauiD· 1 shared Andrés Tapia del FierroiD· 1 shared Andrew KeniryiD· 1 shared Bianca den Hamer· 1 shared Bruno ReversadeiD· 1 shared Dinja van der HoorniD· 1 shared Edwina McGlinniD· 1 shared Fabrice PriniD· 1 shared

Activity by Year

2023-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperMolecular Biology

Alexandra D. GurzauORCID

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1 paper

Recent·Most cited

SMCHD1 has separable roles in chromatin architecture and gene silencing that could be targeted in disease

Andrés Tapia del Fierro, Bianca den Hamer, Natalia Benetti, Natasha Jansz, Kelan Chen, Tamara J Beck, Hannah Kate Vanyai, Alexandra D. Gurzau, Lucia Daxinger, Shifeng Xue, Thanh Thao Nguyen Ly, Iromi Wanigasuriya, Megan Iminitoff, Kelsey A. Breslin, Harald Oey, , Marnie E. Blewitt

This study identifies a mutation in SMCHD1 that enhances gene silencing and disrupts developmental processes, revealing distinct roles of SMCHD1 in chromatin structure and gene regulation.

Nature Communications · Sep 25, 2023Peer-reviewedMolecular Biology