Edwina McGlinn

The paper shows that PRC2 subunits JARID2 and PALI1 mimic H3K27me3 to restrict Polycomb domain spread by antagonizing PRC2 activity in vivo and stem cells.

The paper identifies three genes associated with vertebral variations and chronic pain using UK Biobank data and deep learning.

This study identifies a mutation in SMCHD1 that enhances gene silencing and disrupts developmental processes, revealing distinct roles of SMCHD1 in chromatin structure and gene regulation.

This study shows maternal SMCHD1 prevents premature Hox gene activation in mouse embryos, leading to posterior homeotic transformations when absent.

This study identifies Nr6a1 as a master regulator of trunk-specific axial development in mice, controlling elongation, segmentation, and lineage allocation through Hox gene regulation and gene regulatory networks.

The paper identifies a Hox code that defines molecular regionalisation of spinocerebellar neuron subtypes in the cervico-thoracic spinal cord.

This study identifies Smchd1 as a regulator of long-range chromatin interactions, showing context-dependent effects on transcription and chromatin structure.