Shunsuke Tagami

This study investigates whether prebiotic cationic amino acids like ornithine and diamino butyric acid can support the formation of an ancient protein fold, finding that they can adopt a foldable structure under specific conditions.

This study uses ancestral sequence reconstruction to identify amino acid substitutions responsible for low-temperature adaptation in an enzyme.

The paper identifies and characterizes two RNA polymerases in a thermophilic virus, showing their structural and functional differences and evolutionary origin.