David R. Roalf

Olfactory Deficits and Structural Anomalies of the Peripheral Olfactory System in 22q11.2 Deletion Syndrome

This study investigates olfactory deficits and structural anomalies in the olfactory system among individuals with 22q11.2 deletion syndrome compared to psychosis spectrum and typically developing controls.

An Open Test--Retest Dataset of Rapid Myelin Mapping Acquisitions

The paper introduces a multimodal MRI dataset to evaluate myelin-sensitive imaging methods across test-retest acquisitions and metrics.

Anatomical White Matter Tracts Span the Cortical Hierarchy to Support Cognitive Diversity

The paper shows that white matter tracts are positioned within the cortical hierarchy to support specific cognitive functions and connect regions with greater cognitive diversity.

The PMADS Project: A Longitudinal Multimodal Cohort Study to Understand Risk for Perinatal Mood and Anxiety Disorders

The PMADS Project tracks neurobiological and clinical changes in high-risk individuals across the perinatal period to identify biomarkers linking brain plasticity to PMADs risk.

A longitudinal data resource to study brain development and transdiagnostic variation in executive function

The paper introduces a longitudinal data resource combining multimodal imaging and cognitive phenotyping to study brain development and EF variation in adolescents.

Cannabis Use and Glutamate across the Psychosis Spectrum: In Vivo Evidence from 7T Proton Magnetic Resonance Spectroscopy

This study examines the relationship between cannabis use, glutamate levels in the anterior cingulate cortex, and symptom severity across the psychosis spectrum using 7T proton magnetic resonance spectroscopy.

An open, fully-processed data resource for studying mood and sleep variability in the developing brain

The paper introduces an open data resource combining neuroimaging and behavioral measures to study mood and sleep in adolescents and young adults.

Two Axes of White Matter Development

This study identifies two axes of white matter development in human cortico-cortical tracts using diffusion MRI across three datasets, revealing non-uniform maturation patterns.

Benchmarking Orientation Distribution Function Estimation Methods for Tractometry in Single-Shell Diffusion Magnetic Resonance Imaging - An Evaluation of Test-Retest Reliability and Predictive Capability

This paper evaluates ODF reconstruction methods for single-shell dMRI, finding SS3T provides reliable and predictive WM bundle segmentation with lower angular resolution data.

A systematic protocol to identify 'clinical controls' for pediatric neuroimaging research from clinically acquired brain MRIs

Reproducible Sex Differences in Personalized Functional Network Topography in Youth

The paper identifies robust sex differences in personalized functional brain network topography in youth, linked to X-linked genes and brain regions involved in psychiatric disorders.

A sensorimotor-association axis of thalamocortical connection development

The paper shows thalamocortical connections develop along a sensorimotor-association gradient in youth, linking structural connectivity to cortical plasticity and environmental sensitivity.

Network Enrichment Significance Testing in Brain-Phenotype Association Studies

The paper introduces NEST, a framework for testing brain-phenotype associations within functional networks, applied to neurodevelopmental imaging data.

Diffusion MRI Head Motion Correction Methods are Highly Accurate but Impacted by Denoising and Sampling Scheme

This study evaluates head motion correction methods in diffusion MRI, showing both Eddy and SHORELine perform well but are affected by denoising and sampling schemes.

Development of White Matter Fiber Covariance Networks Supports Executive Function in Youth

This study identifies white matter fiber covariance networks in youth, showing their development aligns with executive function and hierarchical cortical maturation patterns.

Establishing the Validity of Compressed Sensing Diffusion Spectrum Imaging

This study evaluates six compressed sensing diffusion spectrum imaging (CS-DSI) schemes, finding they provide accurate and reliable white matter structure measures with up to 80% reduced scan time compared to full DSI.

Individual Differences in Delay Discounting are Associated with Dorsal Prefrontal Cortex Connectivity in Youth

This study links individual differences in delay discounting to specific patterns of dorsal prefrontal cortex connectivity in youth using resting-state fMRI.

Asymmetric Signaling Across the Hierarchy of Cytoarchitecture within the Human Connectome

The paper uses network control theory to show that bottom-up signaling across the sensory-fugal axis of the human connectome requires less energy than top-down signaling.

Compression supports low-dimensional representations of behavior across neural circuits

The paper uses network theory to predict compression levels in neural circuits and finds differences in dimensionality and representational capacity across brain regions and behaviors.

Personalized Functional Brain Network Topography Predicts Individual Differences in Youth Cognition

The paper defines personalized functional networks in children to predict cognitive differences, finding that fronto-parietal network representation correlates with general cognition.

Intrinsic Activity Develops Along a Sensorimotor-Association Cortical Axis in Youth

The paper shows that intrinsic brain activity decreases along a sensorimotor-association cortical axis during human development, with reduced activity in disadvantaged youth.

ModelArray: a memory-efficient R package for statistical analysis of fixel data

ModelArray is an R package for efficient statistical analysis of fixel data, supporting linear and nonlinear models with reduced memory usage.

Voxel-wise Intermodal Coupling Analysis of Two or More Modalities using Local Covariance Decomposition

This paper introduces a method to analyze intermodal coupling between multiple brain imaging modalities and applies it to study neurodevelopmental patterns in adolescents.

Mobile Footprinting: Linking Individual Distinctiveness in Mobility Patterns to Mood, Sleep, and Brain Functional Connectivity

This study links individual mobility patterns to mood, sleep, and brain connectivity by identifying unique mobility footprints.

Developmental coupling of cerebral blood flow and fMRI fluctuations in youth

This study examines how cerebral blood flow and fMRI fluctuations are coupled in youth, finding age-related decreases, sex differences, and links to executive function.

A Developmental Reduction of the Excitation:Inhibition Ratio in Association Cortex during Adolescence.

This study uses pharmacological fMRI to show a reduction in the excitation:inhibition ratio in association cortex during adolescence, linked to psychopathology.

Network controllability mediates the relationship between rigid structure and flexible dynamics

The paper investigates how structural brain networks influence functional dynamics through network controllability, finding that boundary controllability mediates the relationship between structural participation and functional flexibility.

Efficient Coding in the Economics of Human Brain Connectomics

The paper develops a theory of efficient coding in brain networks and shows that structural connectivity balances information fidelity and compression, predicting behavior and explaining biological organization.

Altered functional brain dynamics in chromosome 22q11.2 deletion syndrome during facial affect processing

This study identifies altered functional brain dynamics in 22q11.2DS during facial affect processing using fMRI, showing preserved early visual and insular activation but diminished motor feedback and emotional memory signals.

Association between Neighborhood Socioeconomic Status and Executive System Activation in Youth

This study examines how neighborhood socioeconomic status affects executive system activation during a working memory task in youth and identifies mediating brain activity patterns.