Author

Nicholas L Bayhi

University of ChicagoORCID 0000-0002-1735-7829Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:cryo-EM· 1 Approach:deep learning· 1 Organism:human· 1 Approach:mechanistic / dynamical model· 1 Research Focus:protein folding & dynamics· 1 Assay:protein structure· 1 Approach:statistical model· 1

Frequent Co-Authors

Bridget CarragheriD· 1 shared Clinton S PotteriD· 1 shared Hui Alex WeiiD· 1 shared Jordan M MancliD· 1 shared Joshua H. MendeziD· 1 shared Tobin R. SosnickiD· 1 shared Wei-Jen TangiD· 1 shared Wenguang G. LiangiD· 1 shared

Activity by Year

2024-2024 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 36 mutual co-author links

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1 shared paperBiophysics

Bridget CarragherORCID

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1 paper

Recent·Most cited

Characterization and modulation of human insulin degrading enzyme conformational dynamics to control enzyme activity

Jordan M Mancl, Wenguang G. Liang, Nicholas L Bayhi, Hui Alex Wei, William C. Budell, Joshua H. Mendez, Tobin R. Sosnick, Bridget Carragher, Clinton S Potter, Wei-Jen Tang

This study characterizes IDE conformational dynamics using cryo-EM and MD simulations, identifying key residues and mechanisms that modulate enzyme activity.

bioRxiv · Dec 30, 2024Biophysics