Clinton S. Potter

This study characterizes IDE conformational dynamics using cryo-EM and MD simulations, identifying key residues and mechanisms that modulate enzyme activity.

This study uses time-resolved cryo-EM to visualize early intermediates in bacterial RNA polymerase promoter melting, revealing key steps in the formation of the transcription-competent open complex.

This study examines how data compression and lossy image formats affect cryoEM reconstruction quality, finding that compressed data can still yield sub-2Å reconstructions.

The paper reduces particle adsorption to air-water interfaces in cryoEM using Spotiton robot and nanowire grids, demonstrated on three biological samples.

The paper benchmarks cryo-EM single particle analysis workflows using a standard sample and procedures to ensure high-resolution map production.

The paper describes new features and applications of Spotiton, a cryoEM sample vitrification instrument, showing it produces high-quality specimens with no apparent sample damage.