Luke Potter

This study shows that transiently increased cardiomyocyte O-GlcNAcylation worsens cardiac remodeling after pressure overload, supporting the concept of O-GlcNAc memory as part of metabolic memory.

nf_xpatial provides a standardized Nextflow pipeline for preprocessing and clustering Xenium spatial transcriptomics data, enabling reproducible analysis and parameter comparison.

The paper identifies a rare striatal neuron population, Chst9-MSNs, that is critical for opioid reward and distinct from canonical pathways.