Olivia R. Drake

nf_xpatial provides a standardized Nextflow pipeline for preprocessing and clustering Xenium spatial transcriptomics data, enabling reproducible analysis and parameter comparison.

The paper identifies a rare striatal neuron population, Chst9-MSNs, that is critical for opioid reward and distinct from canonical pathways.

This study shows that heroin relapse triggered by drug cues persists for over a year in abstinent rats, indicating long-term vulnerability to opioid relapse.

The paper identifies a conserved enhancer upstream of Pdyn that is regulated by activity-dependent transcription factors and required for Pdyn expression in neurons.

The paper establishes a mouse model of incubation of palatable food craving and identifies brain-wide activation patterns using whole-brain activity mapping.