Author

Wolfgang Jarolimek

Pharmaxis (Australia)ORCID 0000-0002-1757-5420Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 2 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:bulk RNA-seq· 2 Research Focus:cancer & tumor microenvironment· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:clustering· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Lara PerrymaniD· 3 shared Alicia F. C. OkinesiD· 1 shared Amelie ZiehmeiD· 1 shared Amna Zahoor· 1 shared Anya A NicholasiD· 1 shared Athina Stavrodimou· 1 shared Beatrice A. HowardiD· 1 shared Beatrice MalacridaiD· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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3 shared papersCancer Biology

Lara PerrymanORCID

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3 papers

Recent·Most cited

Cancer BiologyiSciencePeer-reviewedFeb 9, 2026

Matrix structure and microenvironment dynamics correlate with chemotherapy response in ovarian cancer

Florian Laforêts, Panoraia Kotantaki, Samar Elorbany…·Frances R. Balkwill

The paper shows that modifying the tumor microenvironment's extracellular matrix improves chemotherapy response in ovarian cancer models.

2 citationstop 3%

mousebulk RNA-seq

𝕏 PostBluesky

Cancer BiologybioRxivPreprintAug 27, 2025

LOX inhibition disrupts a collagen-integrin-MYC axis as a translatable targeting strategy in invasive lobular carcinoma

Renée L. Flaherty, Flavia Hughes, George Sflomos…·Cathrin Brisken

LOX inhibition disrupts a collagen-integrin-MYC axis in ILC, halting tumor growth and metastasis with minimal toxicity, offering a new therapeutic strategy.

DOI 10.1101/2025.08.27.672618

humanbulk RNA-seq

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Molecular BiologybioRxivPreprintJul 6, 2023

Accurate quantification of lysyl oxidase concentration in human tissue

Yimin Yao, Lara Perryman, Amna Zahoor…·Wolfgang Jarolimek

This study develops a sensitive and accurate digital ELISA to measure LOX concentration in human serum, showing higher levels in bladder cancer patients compared to healthy controls.

DOI 10.1101/2023.07.06.548012

humanproteomics

𝕏 PostBluesky