BiochemistrybioRxivPreprint
Tandem bromodomains of BRD4 cooperatively read poly-acetylated nucleosomes to enhance chromatin engagement and regulate breast cancer phenotypes
Nathaniel T. Burkholder, Shwu-Yuan Wu, Jackson Handy…·Brian D. Strahl
This study shows that BRD4's tandem bromodomains cooperatively bind poly-acetylated nucleosomes, enhancing chromatin engagement and influencing breast cancer phenotypes.