Author

Todd Z. DeSantis

Second Genome (United States)ORCID 0000-0002-1786-1013Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:database / resource· 2 Assay:metagenomics· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1 Organism:human· 1 Assay:metabolomics· 1

Frequent Co-Authors

Aki Samuli HavulinnaiD· 1 shared Andrew P. BartkoiD· 1 shared Antonio GonzáleziD· 1 shared Brianna ChrismaniD· 1 shared Christine A. TataruiD· 1 shared Daniel T. McDonaldiD· 1 shared Dennis Paul WalliD· 1 shared Donovan H. ParksiD· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperBioinformatics

Aki Samuli HavulinnaORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Topic modeling for multi-omic integration in the human gut microbiome and implications for autism

Christine A. Tataru, Marie Peras, Erica M. Rutherford, Kaiti Dunlap, Xiaochen Yin, Brianna Chrisman, Todd Z. DeSantis, Dennis Paul Wall, Shoko Iwai, Maude M. David

This study uses topic modeling to integrate multi-omic data from the gut microbiome of children with and without autism, identifying microbial processes associated with autism.

Scientific Reports · Jul 13, 2023Peer-reviewedBioinformatics

Greengenes2 enables a shared data universe for microbiome studies

Daniel T. McDonald, Yueyu Jiang, Metin Balaban, Kalen Cantrell, Qiyun Zhu, Antonio González, James T. Morton, Giorgia Nicolaou, Donovan H. Parks, Søren Michael Karst, Mads Albertsen, Philip Hugenholtz, Todd Z. DeSantis, Se Jin Song, Andrew P. Bartko, , Rob D. Knight

Greengenes2 aligns 16S rRNA and shotgun metagenomic data using a whole-genome phylogeny, showing agreement in principal coordinates, taxonomy, and phenotype effect size.

bioRxiv · Dec 19, 2022 · PreprintBioinformatics