Author

Krithika P. Karthigeyan

Weill Cornell MedicineORCID 0000-0002-1808-6688Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Immunology· 2 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Organism:human· 2 Assay:proteomics· 2 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1

Frequent Co-Authors

Chelsea M. CrooksiD· 3 shared Jason S. McLellaniD· 3 shared Sallie R. PermariD· 3 shared Adelaide S. FulleriD· 2 shared Ajit R. RamamohaniD· 2 shared Caitlin A. WilliamsiD· 2 shared Christian R. BinuyaiD· 2 shared Dong Liang YuiD· 2 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersImmunology

Chelsea M. CrooksORCID

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3 papers

Recent·Most cited

ImmunologybioRxivPreprintOct 19, 2026

B cell response to HCMV gH/UL116 elicits neutralizing and FcγR-activating antibodies

Artem Ashurov, Katja Hoffmann, Ajit R. Ramamohan…·Matthias Zehner

The paper identifies gH/UL116 as a target for antibodies that neutralize HCMV and activate FcγR, showing its potential as a vaccine candidate.

DOI 10.64898/2026.10.11.758335

humanproteomics

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ImmunologyJournal of VirologyPeer-reviewedMay 8, 2025

A human cytomegalovirus prefusion-like glycoprotein B subunit vaccine elicits similar humoral immunity to that of postfusion gB in mice

Krithika P. Karthigeyan, Megan Connors, Christian R. Binuya…·Sallie R. Permar

This study compares humoral immunity elicited by prefusion-like and postfusion forms of HCMV gB in mice, finding similar neutralization titers but differences in antibody binding and phagocytosis.

17 citationstop 1%

mouseproteomics

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Molecular BiologyProceedings of the National Academy of SciencesPeer-reviewedSep 4, 2024

Structure-based design of a soluble human cytomegalovirus glycoprotein B antigen stabilized in a prefusion-like conformation

Madeline R. Sponholtz, Patrick O. Byrne, Alison G. Lee…·Jason S. McLellan

This paper describes the stabilization of HCMV gB in a prefusion-like conformation using structure-based design and shows similar neutralizing antibody titers against postfusion and prefusion forms.

37 citationstop 1%

humanprotein structure

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