Robert E. Van Sciver

This study identifies ciliary ARL13B's GEF activity as a driver of Pkd1-dependent renal cystogenesis in mice.

This paper shows that expressing ARL13B-Cerulean rescues Arl13b-null mice from embryonic lethality but not fertility, indicating ARL13B's role in spermatogenesis.

This study shows that ARL13B in cilia inhibits kidney cyst formation in mice, and this function is independent of its role as a GEF for ARL3.

This study identifies functionally conserved roles of Drosophila SINA and human SIAH1/2 in RAS/EGFR pathway regulation, showing their efficacy in blocking neuronal cell fate determination in Drosophila.