Author

Omar Youssef

University of HelsinkiORCID 0000-0002-1827-9156Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Organism:mouse· 1 Assay:spatial transcriptomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Agnieszka WoźniakiD· 1 shared Andrew M. EricksoniD· 1 shared Anna Ray LauryiD· 1 shared Astrid MurumägiiD· 1 shared Chao‐Chi WangiD· 1 shared Franziska NiemeyeriD· 1 shared Harri J. SihtoiD· 1 shared Jorma J IsolaiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperMolecular Biology

Agnieszka WoźniakORCID

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2 papers

Recent·Most cited

Spatial transcriptomics reveals interferon pathway enrichment in early relapsing serous carcinoma

Franziska Niemeyer, Niina Aho, Satu M. Hänninen, Omar Youssef, Olli Carpén, Andrew M. Erickson, Anna Ray Laury

This study uses spatial transcriptomics to identify interferon pathway enrichment in early relapsing high-grade serous carcinoma, linking it to poor prognosis and suggesting C3 as a biomarker.

bioRxiv · Oct 13, 2026 · PreprintCancer Biology

Phosphodiesterase 3A modulators sensitize tumor cells to Bcl-xL and Bcl-2/Bcl-xL inhibitors

Kirsi Toivanen, Astrid Murumägi, Agnieszka Woźniak, Karo Wyns, Chao‐Chi Wang, Luna De Sutter, Mariliina Arjama, Nanna Merikoski, Sami Salmikangas, Omar Youssef, Jorma J Isola, Olli Kallioniemi, Patrick Schöffski, Tom Böhling, Harri J. Sihto

This study identifies PDE3A modulators that synergize with Bcl-xL and Bcl-2/Bcl-xL inhibitors to induce tumor regression in sarcoma models.

bioRxiv · Apr 10, 2025 · PreprintMolecular Biology