Author

Jorma Isola

Tampere UniversityORCID 0000-0002-0849-5939Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1

Frequent Co-Authors

Agnieszka WoźniakiD· 1 shared Alka GuptaiD· 1 shared Astrid MurumägiiD· 1 shared Chao‐Chi WangiD· 1 shared Chen ChongthamiD· 1 shared Diana M. ToivolaiD· 1 shared Diego BalboaiD· 1 shared Eriika SavontausiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperMolecular Biology

Agnieszka WoźniakORCID

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2 papers

Recent·Most cited

Scinderin-driven Golgi Actin Remodeling coordinates GLP-1 and insulin secretion to regulate glucose homeostasis

Laura Martín-Díaz, Maarit S. Patrikainen, Chen Chongtham, Alka Gupta, Valeriia Dotsenko, M Ojanen, Fábio Tadeu Arrojo Martins, Joel Johnson George, Roselia Davidsson, Satu Hakanen, Kim Eerola, Eriika Savontaus, Jonna Saarimäki‐Vire, Diego Balboa, Jorma Isola, , Keijo M. Viiri

This study identifies Scinderin as a regulator of Golgi actin remodeling that coordinates GLP-1 and insulin secretion, linking intracellular trafficking defects to glucose homeostasis and diabetes.

bioRxiv · May 28, 2026 · PreprintCell Biology

Phosphodiesterase 3A modulators sensitize tumor cells to Bcl-xL and Bcl-2/Bcl-xL inhibitors

Kirsi Toivanen, Astrid Murumägi, Agnieszka Woźniak, Karo Wyns, Chao‐Chi Wang, Luna De Sutter, Mariliina Arjama, Nanna Merikoski, Sami Salmikangas, Omar Youssef, Jorma J Isola, Olli Kallioniemi, Patrick Schöffski, Tom Böhling, Harri J. Sihto

This study identifies PDE3A modulators that synergize with Bcl-xL and Bcl-2/Bcl-xL inhibitors to induce tumor regression in sarcoma models.

bioRxiv · Apr 10, 2025 · PreprintMolecular Biology