Author

Albert William Garofalo

Stanford UniversityORCID 0000-0002-1837-417XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Marc Adler· 1 shared Marcus D. SchonemanniD· 1 shared Matteo SantoroiD· 1 shared Thomas Jude MontineiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

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4 top collaborators · 6 mutual co-author links

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1 shared paperBiochemistry

Marc Adler

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1 paper

Recent·Most cited

BiochemistrybioRxivPreprintOct 28, 2026

Novel LRRK2 Kinase Inhibitors Enhance Phosphorylation and Restore Adapter Protein Binding in LRRK2 Variants

Albert William Garofalo, Marcus D. Schonemann, Matteo Santoro…·Thomas Jude Montine

This study evaluates two series of LRRK2 inhibitors, showing that series B compounds enhance phosphorylation and restore 14-3-3 binding in LRRK2 variants, suggesting conformation-selective inhibition as a potential PD therapy.

DOI 10.64898/2026.10.26.762006

humanexperimental assay

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