Author

Marc Adler

Stanford University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:human· 2

Frequent Co-Authors

Aidan KeithiD· 1 shared Albert William GarofaloiD· 1 shared Changliang He· 1 shared Dominique C. MitchelliD· 1 shared Gary K.L. ChaniD· 1 shared Jin Liu· 1 shared John Dozier GordaniD· 1 shared Jonathan M. L. OstremiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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1 shared paperBiochemistry

Aidan KeithORCID

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2 papers

Recent·Most cited

Novel LRRK2 Kinase Inhibitors Enhance Phosphorylation and Restore Adapter Protein Binding in LRRK2 Variants

Albert William Garofalo, Marcus D. Schonemann, Matteo Santoro, Marc Adler, Thomas Jude Montine

This study evaluates two series of LRRK2 inhibitors, showing that series B compounds enhance phosphorylation and restore 14-3-3 binding in LRRK2 variants, suggesting conformation-selective inhibition as a potential PD therapy.

bioRxiv · Oct 28, 2026 · PreprintBiochemistry

Small molecule activation of the tumor suppressor kinase LKB1

Lin Song, Dominique C. Mitchell, Jin Liu, Logan B. Leak, Rigney E. Turnham, LeeAnn Wang, Zheng Wang, Changliang He, Luo Ding, Marc Adler, Timothy Kellett, Aidan Keith, Yeonjoo C Hwang, Gary K.L. Chan, Robert L. G. Gottschalk, , John Dozier Gordan

This study develops small molecules that activate the tumor suppressor kinase LKB1 and shows their therapeutic benefits in cancer cell lines.

Cell chemical biology · Aug 1, 2026Peer-reviewedBiochemistry