Author
National University of SingaporeORCID 0000-0002-1837-8330Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
Nanhai Jiang, Yang Wu, Steve Rozen
The paper benchmarks 13 mutational signature attribution tools, including a new method called PASA, on synthetic data to evaluate their performance across different cancer types.
Mo Liu, Yang Wu, Nanhai Jiang…·Steve Rozen
mSigHdp improves mutational signature discovery using hierarchical Dirichlet process mixture models, outperforming NMF-based methods on synthetic data.
S. M. Ashiqul Islam, Marcos Díaz‐Gay, Yang Wu…·Ludmil B. Alexandrov
SigProfilerExtractor is a tool for de novo mutational signature extraction that outperforms existing methods and identifies four novel signatures, including one linked to tobacco smoking.