Author

S. M. Ashiqul Islam

Baylor UniversityORCID 0000-0002-5686-6474Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:variant calling· 2 Assay:whole-exome sequencing· 2 Assay:whole-genome sequencing· 2 Approach:benchmark study· 1 Approach:experimental assay· 1

Frequent Co-Authors

Christopher Michel KearneyiD· 2 shared Ludmil B. AlexandroviD· 2 shared Marcos Díaz‐GayiD· 2 shared Mark D. BarnesiD· 2 shared Michael R. StrattoniD· 2 shared Paul BrennaniD· 2 shared Raviteja VangaraiD· 2 shared Sarah MoodyiD· 2 shared

Activity by Year

2017-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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Curved chords = mutual co-authorship

2 shared papersMolecular Biology

Christopher Michel KearneyORCID

Author profile →

4 papers

Recent·Most cited

Assigning mutational signatures to individual samples and individual somatic mutations with SigProfilerAssignment

Marcos Díaz‐Gay, Raviteja Vangara, Mark D. Barnes, Xi Wang, S. M. Ashiqul Islam, Ian Vermes, Stephen Oscar Duke, Nithish Bharadhwaj Narasimman, Ting Yang, Zichen Jiang, Sarah Moody, Sergey Senkin, Paul Brennan, Michael R. Stratton, Ludmil B. Alexandrov

SigProfilerAssignment refits known substitution, doublet, indel and copy-number mutational signatures to single samples and probabilistically to individual mutations, outperforming four refitting tools on 2,700 synthetic genomes.

Bioinformatics · Dec 1, 2023Peer-reviewedBioinformatics✦ In-depth digest

Uncovering novel mutational signatures by de novo extraction with SigProfilerExtractor

S. M. Ashiqul Islam, Marcos Díaz‐Gay, Yang Wu, Mark D. Barnes, Raviteja Vangara, Erik N. Bergstrom, Yudou He, Mike Vella, Jingwei Wang, Jon W. Teague, Peter Clapham, Sarah Moody, Sergey Senkin, Yun Rose Li, Laura Riva, , Ludmil B. Alexandrov

SigProfilerExtractor is a tool for de novo mutational signature extraction that outperforms existing methods and identifies four novel signatures, including one linked to tobacco smoking.

Cell Genomics · Sep 23, 2022Peer-reviewedBioinformatics

The use of a virus-derived targeting peptide to selectively kill staphylococcus bacteria with antimicrobial peptides

Ankan Choudhury, S. M. Ashiqul Islam, Meron R. Ghidey, Christopher Michel Kearney

The paper fuses bacteriophage-derived targeting peptides to antimicrobial peptides to selectively kill Staphylococcus bacteria, showing reduced toxicity against non-target species.

Biotechnology Letters · Dec 4, 2019Peer-reviewedMolecular Biology

Protein classification using modified n-gram and skip-gram models

S. M. Ashiqul Islam, Benjamin J. Heil, Christopher Michel Kearney, Erich J. Baker

This study introduces a modified N-Gram and Skip-Gram model for protein classification from primary sequence data, showing improved accuracy over existing methods.

Bioinformatics · Dec 21, 2017Peer-reviewedBioinformatics