Michael Druzin

This study shows that O-GlcNAc transferase (OGT) regulates inhibitory synapse structure and GABAA receptor composition by modulating synaptic morphology and subunit expression.

This study shows that OGT regulates excitatory synaptic plasticity in PVN CaMKII neurons, linking metabolic state to satiation signaling through changes in synaptic input resistance and activity during feeding and hunger.

This study shows that heparan sulfates regulate axonal excitability and context generalization via CaMKII, with heparinase treatment affecting neuronal function and memory.

This study shows that extracellular matrix degradation reduces KCC2 protein levels, increases intracellular chloride concentration, and alters GABAergic transmission in rat neurons.