Olof Lagerlöf

This study shows O-GlcNAcase promotes dendritic spine maturation and increases spine density while reducing GluA2-containing AMPA receptors in neurons.

This study shows that O-GlcNAc transferase (OGT) regulates inhibitory synapse structure and GABAA receptor composition by modulating synaptic morphology and subunit expression.

This study shows that OGT regulates excitatory synaptic plasticity in PVN CaMKII neurons, linking metabolic state to satiation signaling through changes in synaptic input resistance and activity during feeding and hunger.

The paper identifies somatostatine interneurons as key mediators of dopamine-dependent sensory gating in the orbitofrontal cortex, showing their role in suppressing the second response to paired sounds.