Author

Manish Bhattacharjee

Umeå UniversityORCID 0000-0002-9271-8663Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 2 Research Focus:cell type annotation· 1 Assay:electronic health records· 1

Frequent Co-Authors

Olof LagerlöfiD· 3 shared Linkun HaniD· 2 shared Mario Pérez Del PozoiD· 2 shared Michael DruziniD· 2 shared Sabrina Galizia· 2 shared Anushree Tripathi· 1 shared Carla BlancoiD· 1 shared Jingyu PaniD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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3 shared papersNeuroscience

Olof LagerlöfORCID

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3 papers

Recent·Most cited

O-GlcNAcase promotes dendritic spine morphogenesis while downregulating their GluA2-containing AMPA receptors

Linkun Han, Sabrina Galizia, Jingyu Pan, Manish Bhattacharjee, Olof Lagerlöf

This study shows O-GlcNAcase promotes dendritic spine maturation and increases spine density while reducing GluA2-containing AMPA receptors in neurons.

Journal of Biological Chemistry · Jan 13, 2026Peer-reviewedNeuroscience

O-GlcNAc Transferase Regulates GABAergic Synapse Organization and Receptor Composition.

Manish Bhattacharjee, Linkun Han, Petya Elenska, Mario Pérez Del Pozo, Carla Blanco, Michael Druzin, Olof Lagerlöf

This study shows that O-GlcNAc transferase (OGT) regulates inhibitory synapse structure and GABAA receptor composition by modulating synaptic morphology and subunit expression.

bioRxiv · Nov 21, 2025 · PreprintNeuroscience

Satiation is associated with OGT-dependent regulation of excitatory synapses.

Mario Pérez Del Pozo, Manish Bhattacharjee, Anushree Tripathi, Thyra Boafo, Sabrina Galizia, Paolo Medini, Michael Druzin, Olof Lagerlöf

This study shows that OGT regulates excitatory synaptic plasticity in PVN CaMKII neurons, linking metabolic state to satiation signaling through changes in synaptic input resistance and activity during feeding and hunger.

bioRxiv · Sep 2, 2025 · PreprintNeuroscience