Isaäc J. Nijman

The paper develops predictive models using patient-derived breast cancer organoids to identify drug responses and guide new therapies for resistant disease.

The paper uses spatial transcriptomics to analyze the insular cortex of schizophrenia patients and controls, identifying metabolic changes in the blood-brain barrier and parenchyma.

This study analyzes Y-chromosomal haplotypes in domestic, ancient, and wild goats to reconstruct their population history and phylogeographic patterns.

This study identifies novel HPE genes and oligogenic inheritance patterns in holoprosencephaly by integrating clinical data with exome sequencing and gene prioritization.