Spatial Transcriptomics of Schizophrenia Insular Cortex Reveals Blood-Brain Barrier Hyperglycolysis and Increased Parenchymal Mitochondrial Respiration
Karin Huizer, Vera van Dis, Thao Tran, Pieter Roberto Bakker, Marc Claesen, Isaäc J. Nijman, Robin Geene, Nico J.M. van Beveren, Dana A. M. Mustafa
The paper uses spatial transcriptomics to analyze the insular cortex of schizophrenia patients and controls, identifying metabolic changes in the blood-brain barrier and parenchyma.
bioRxiv · Mar 12, 2025 · PreprintNeuroscience