Author

Jonathan M. Ellis

University of North Carolina at Chapel HillORCID 0000-0002-1845-8461Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Assay:proteomics· 1

Frequent Co-Authors

Albert A. BowersiD· 1 shared Amelia C. McCueiD· 1 shared Brian A. KuhlmaniD· 1 shared Christopher ShelbyiD· 1 shared Kaylee P. KuzelkaiD· 1 shared Rodney ParkiD· 1 shared Satish K. NairiD· 1 shared Zhiyuan YaoiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 28 mutual co-author links

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1 shared paperBiochemistry

Albert A. BowersORCID

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1 paper

Recent·Most cited

Enhancing enzymatic bioconjugation efficiency via installation of a substrate recruitment domain

Christopher Shelby, Kaylee P. Kuzelka, Jonathan M. Ellis, Zhiyuan Yao, Amelia C. McCue, Rodney Park, Satish K. Nair, Albert A. Bowers, Brian A. Kuhlman

The paper designs a modified tyrosinase enzyme with a substrate recruitment domain to selectively modify tyrosine residues in peptides, enabling efficient bioconjugation of cytotoxic molecules to antibodies.

bioRxiv · Oct 27, 2025 · PreprintBiochemistry