Author
Pennsylvania State UniversityORCID 0000-0002-1846-5469Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
Yiyun Rao, Ivan Sokirniy, Edward P. O’Brien, Justin R. Pritchard
The paper validates that synonymous mutations in the human genome rarely affect fitness, occurring 165-fold less frequently than non-synonymous mutations.
Ivan Sokirniy, Haider Inam, Marta Tomaszkiewicz…·Justin R. Pritchard
This study compares deep mutational scanning and CRISPR base editing for variant function annotation, finding strong correlation between base editor data and gold standard DMS results.
Xuanyu Chen, Ivan Sokirniy, Xin Wang…·Hedong Li
This study identifies miR-375 as a factor that enhances astrocyte-to-neuron reprogramming by promoting cell survival during the process.