Author

Xuanyu Chen

Augusta UniversityORCID 0000-0003-0007-5398Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:differential expression· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:cell-cell communication· 2 Approach:experimental assay· 2 Organism:human· 2 Organism:mouse· 2 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Christine Williams· 2 shared Hedong LiiD· 2 shared Mei Hua JiangiD· 2 shared Natalie Mseis-JacksoniD· 2 shared Arya Ranchod· 1 shared Brendan Puls· 1 shared Feitai Tang· 1 shared Ge LiniD· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersNeuroscience

Christine Williams

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3 papers

Recent·Most cited

GeneticsbioRxivPreprintAug 4, 2026

Non-Invasive Embryo Quality Assessment via Matrix-Optimized Untargeted LC-MS Metabolomics of Spent Embryo Culture Media and Weighted Ensemble Machine Learning

Huimin Gan, Xingyao Wang, Feitai Tang…·Shen Zhang

This paper develops a non-invasive method for embryo quality assessment using metabolomics of spent culture media and machine learning, identifying metabolic signatures linked to ploidy and morphology.

DOI 10.64898/2026.07.30.741666

humanmetabolomics

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NeuroscienceMolecular Therapy — Nucleic AcidsPeer-reviewedSep 5, 2025

Dynamic regulation of NeuroD1 expression level by a novel viral construct during astrocyte-to-neuron reprogramming

Natalie Mseis-Jackson, Mei Hua Jiang, Mehek Sharma…·Hedong Li

This study introduces a viral construct that dynamically regulates NeuroD1 expression during astrocyte-to-neuron reprogramming, reducing its level in reprogrammed neurons to enhance GABAergic differentiation.

3 citations

mousebulk RNA-seq

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NeuroscienceCellsPeer-reviewedSep 3, 2023

MicroRNA-375 is induced during astrocyte-to-neuron reprogramming and promotes survival of reprogrammed neurons when overexpressed

Xuanyu Chen, Ivan Sokirniy, Xin Wang…·Hedong Li

This study identifies miR-375 as a factor that enhances astrocyte-to-neuron reprogramming by promoting cell survival during the process.

9 citations

humanmouse

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