Orc4 spatiotemporally stabilizes centromeric chromatin
Lakshmi Sreekumar, Kiran Kumari, Krishnendu Guin, Asif Bakshi, Neha Varshney, Bhagya C. Thimmappa, Leelavati Narlikar, Ranjith Padinhateeri, Rahul Siddharthan, Kaustuv Sanyal
This study shows Orc4 stabilizes centromeric chromatin by interacting with CENPA and Mcm2, and its spatiotemporal localization is crucial for kinetochore stability in C. albicans.
bioRxiv · Sep 25, 2019Molecular Biology