Neha Varshney

A tissue-targeted auxin-inducible degradation toolkit for C. elegans embryogenesis

The paper develops a tissue-targeted auxin-inducible degradation toolkit for C. elegans embryogenesis and shows that LET-502 degradation in the epidermis disrupts elongation, with unexpected roles in both early and late stages.

Inhibitor-2 directs formation of PP1 holoenzymes through a docking motif-dependent transfer of catalytic subunits to adapters

The paper shows Inhibitor-2 facilitates PP1 holoenzyme formation by transferring catalytic subunits to adapters via its RVxF docking motif, with mutations disrupting this process.

Orc4 spatiotemporally stabilizes centromeric chromatin

This study shows Orc4 stabilizes centromeric chromatin by interacting with CENPA and Mcm2, and its spatiotemporal localization is crucial for kinetochore stability in C. albicans.