Author

Clyde A. Smith

SLAC National Accelerator LaboratoryORCID 0000-0002-1885-1511Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 2

Signature Assays, Organisms & Methods

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Assay:protein structure· 2 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1 Research Focus:protein folding & dynamics· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

Ailiena O. MaggioloiD· 1 shared Aina E. CoheniD· 1 shared Alexander DeitersiD· 1 shared Anastasiya StasyukiD· 1 shared Chasity P. Janosko· 1 shared Guillermo A. CaleroiD· 1 shared Márta TóthiD· 1 shared Maura E. CharetteiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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1 shared paperBiochemistry

Ailiena O. MaggioloORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

BiochemistrybioRxivPreprintJun 29, 2026

CAGE-TRX expands the scope of time-resolved crystallography through genetically encoded active-site photocaging

Clyde A. Smith, Ailiena O. Maggiolo, Chasity P. Janosko…·Aina E. Cohen

The paper introduces CAGE-TRX, a method for time-resolved crystallography that uses photocaged amino acids to control enzyme activity and capture reaction intermediates.

DOI 10.64898/2026.06.26.734858

protein structuregenetic perturbation / CRISPR

𝕏 PostBluesky

BiochemistryACS Infectious DiseasesPeer-reviewedMar 17, 2025

Standardized Residue Numbering and Secondary Structure Nomenclature in the Class D β-Lactamases

Anastasiya Stasyuk, Clyde A. Smith

The paper introduces a standardized residue numbering and secondary structure nomenclature for class D β-lactamases to improve comparative analysis and structural interpretation.

7 citations

protein structureprotein structure prediction

𝕏 PostBluesky