Author

Maura E. Charette

University of PittsburghORCID 0009-0002-7186-4773Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1 Research Focus:protein folding & dynamics· 1 Assay:protein structure· 1

Frequent Co-Authors

Ailiena O. MaggioloiD· 1 shared Aina E. CoheniD· 1 shared Alexander DeitersiD· 1 shared Chasity P. Janosko· 1 shared Clyde A. SmithiD· 1 shared Guillermo A. CaleroiD· 1 shared Márta TóthiD· 1 shared Nilakshi Paul· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperBiochemistry

Ailiena O. MaggioloORCID

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1 paper

Recent·Most cited

CAGE-TRX expands the scope of time-resolved crystallography through genetically encoded active-site photocaging

Clyde A. Smith, Ailiena O. Maggiolo, Chasity P. Janosko, Maura E. Charette, Nilakshi Paul, Márta Tóth, Guillermo A. Calero, Sierra M Carr, Silvia Russi, Sergei B. Vakulenko, Alexander Deiters, Aina E. Cohen

The paper introduces CAGE-TRX, a method for time-resolved crystallography that uses photocaged amino acids to control enzyme activity and capture reaction intermediates.

bioRxiv · Jun 29, 2026 · PreprintBiochemistry