Courtney M. Klappenbach

Androgen depletion increases sensitivity to effort-related costs and alters mesoaccumbal circuit function in male mice

This study shows that androgen depletion in male mice increases sensitivity to effort costs and alters mesoaccumbal circuit function, with distinct effects depending on the timing of hormone loss.

Cell Type-Specific Changes in Dendritic Spines Across Adolescence Within Mouse Medial Prefrontal Cortex

The paper examines dendritic spine changes in mouse medial prefrontal cortex neurons during adolescence, finding greater remodeling in IT-type neurons and a role for microglia.

Sex differences in adolescent cannabis vapor self-administration mediate enduring effects on behavioral flexibility and prefrontal microglia activation in rats

This study shows that adolescent cannabis vapor use leads to lasting effects on behavior and brain structure in female rats, but not males, with higher self-administration rates in females.